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20th SoGAT Meeting

SoGAT XX Presentations

 

Speaker

Title of Talk

Presentation

Session 1: Standardisation science Part 1
Sally Baylis, NIBSC, UK HCV IS study
Harvey Holmes, NIBSC, UK Plans for 2nd reference panel for HIV-1 genotypes and HIV-2 IS
Indira Hewlett, FDA, USA Update from CBER
Micha Nübling, Paul- Ehrlich Institute, Germany Update on WHO projects including anti-HBc
Roberta Madej, Roche, USA HCV synthetic calibrator study
Session 2: Standardisation science Part 2
Michael Chudy, WHO, Switzerland WHO strategic plan for the development of Biological Reference Preparations for blood safety-related IVDs
Ralf Schönbrunner, Acrometrix, USA Practical aspects of standardization for a global controls manufacturer
Mark Manak, SeraCare, USA  Preparation of HIV, HBV and HCV NAT controls: Formulation, Stability and Performance
Saeko Mizusawa, Yoshiaki Okada, National Institute of Infectious Diseases, Japan Establishment of national standards for NAT blood viruses and NAT proficiency program in Japan
Neil Berry, NIBSC, UK  Quantification of SIV RNA and evaluation of infectivity
Cindy Walker-Peach, Asuragen Inc., USA Towards NAT testing in solid tissues and organs: a pre-analytical solution for nucleic acid stabilization
Session 3: EQAS and proficiency studies
Heinz Zeichhardt, Hans-Peter Grunert, Institut fuer Infektionsmedizin, Germany EQAS for TTI diagnostics as tool for elucidating and solving problems of commercial and in-house tests
Wayne Dimech, Thu-Anh Pham, Darren Jardine, Elizabeth Dax , National Serology Reference Laboratory, Australia Monitoring the performance of nucleic acid tests using data generated from EDCNet and DigitalPT
Session 4: Parvovirus B19
Mei-ying Yu, FDA, USA Parvovirus B19 Transmission in transfusion recipients as assessed in a prospective study (TRIPS)
Yi-Chen Yang, Bureau of Food and Drug Analysis, Taiwan Collaborative study for establishment of the first national standard for Parvovirus B19 DNA NAT assays
Jacqueline Fryer, NIBSC, UK Human PARV4 in clotting factor VIII concentrates
Lori Rincknel, Talecris Biotheraputics, USA Identification of novel parvovirus B19 variants
Session 5: Virus variability and HBV
If Barnes, Daniel Candotti, Jean-Pierre Allain, East Anglia Blood Centre, UK

Viral load distribution, BCP/PC mutations and HBV genotypes

Kiyoko Nojima Umemori, Yoshiaki Okada, NIH, Japan Preparation of plasmids containing HBV-full genome of genotype A to H and trial of HBV inactivation method
Piotr Grabarczk, Ewa Brojer, Institute of Haematology and Transfusion Medicine, Poland Anti HBc-detection in ULTRIO not-repeatable reactive blood donors
Hiroshi Yoshizawa, Keiko Katayama, Junko Tanaka, Hiroshima University, Japan Minimum infectious dose of HBV required for establishing infection to human hepatocyte transplanted chimera mice
Michael Chudy, Indira Hewlett, Micha Nübling, Kurt Roth, Peter Simmonds Panel discussion: Impact of virus variability (genotypes) on NAT
Session 6: CMV standardisation and detection
Jutta Preiksaitis, Provlab, Canada

Development of an International Standard for EBV and CMV quantitative viral load assessment

Marcia Holden, NIST, USA NIST Standard Reference Material Project: Pure DNA Standard for Cytomegalovirus
Vivienne James, HPA, UK Update on UK NEQAS external quality assessment for HCV RNA and CMV DNA
Lara Compston, Daniel Candotti, Jean-Pierre Allain, East Anglia Blood Centre, UK Detection and quantification of herpesviruses (CMV, EBV, VZV) and NA viruses (GBV-C, HAV) by Multiplex
Albrecht Groner Round table discussion on IUs vs copies/geqs and conversion factors. Presenters to give pros and cons of using IUs and the appropriateness of converting between IUs and copies
Session 7: NAT new technologies/performance of current technology
Peter Vallone, NIST, USA Developing multiplex PCR assays for human identity testing - is there overlap with pathogen screening?
Lutz Pichl, V Schottstedt, German Red Cross Blood Transfusion Service West, Hagen, Germany Evaluation data on the new Roche COBAS S201 system in combination with the COBAS TaqScreen MPX test
Yiu-Lian Fong, Novartis Vaccines and Diagnostics, USA Performance of Chiron Quantitative and Qualitative HBV PCR and confirmation of HBV Yield Cases
Philip Tuke, UCL, UK HCV window phase infections: Closing the window on HCV. A comparison of two combined antigen/antibody assays with QRT-PCR
Sally Baylis/Philip Minor, NIBSC, UK  NAT standards for clinical virology
Stephen Inglis, NIBSC, UK Future SoGAT meetings and closing remarks