| |
WHO collaborative studies have been undertaken by international
research teams working under the auspicies of the WHO working group
on international reference materials for diagnosis and study of
transmissible spongiform encephalopathies (TSEs)
|
Collaborative Study Participation
Form - Microsoft Word 2000 format (38kb)
|
|
Collaborative Study Participation
Form - Adobe Acrobat Format (pdf) (84kb)
|
|
Meetings Prior, to actual studies
|
Initial meetings on TSE
with WHO, OIE and Working Group on International Reference
Materials For Diagnosis and Study of Transmissible Spongiform
Encephalopathies (TSEs)
|
|
WHO Collaborative Study,
Characterisation
|
To develop reference materials to
facilitate development of methods for diagnosis and better
understandiing of TSE diseases, as well as for the validation of
the ability of pharmaceutical proceduress to remove the
agents.
|
|
WHO Collaborative CJD study
(Nomenclature)
|
To determine the typing and nomenclature
of CJD preparations by criteria including banding on Western
Blot.
|
|
Blood Reference Materials For TSE
Testing
|
To investigate the characteristics of
preparations of human plasma spiked with human
brain.
|
|
Spleen Reference Materials For TSE
Testing
|
To investigate the characteristics of
preparations of human Spleen.
|
|
Evaluation of sensitivity for the detection of PrPsc in
various spiked plasma samples.
|
To evaluate the sensitivity of various
spiked human plasma preparations.
|
|
Evaluation of spiked plasma samples to evaluate
diagnostic tests.
|
To evaluate spiked human plasma
preparations.
|
|
Analysis of scrapie blood/ blood
components.
|
To evaluate sheep blood/ blood
components for use in diagnostic assays.
|
|
Tonsil testing Validation
Study
|
Validation of current diagnostic assays
for Tonsil tissue.
|
|
Plasma testing Validation
Study
|
Validation of current diagnostic assays
for Human Plasma.
|
|
Meetings/ documentation since
studies
|
WHO communications
|
** ongoing
collaboration
|