Publications

SJ Thorpe. Detection of Rh D-associated epitopes in human and animal tissues using human monoclonal anti-D antibodies. Br J Haematol 73, 527-536 (1989).
SJ Thorpe. Reactivity of a human monoclonal antibody against Rh D with the intermediate filament protein vimentin. Br J Haematol 76, 116-120 (1990).
SJ Thorpe, SW Bailey, HC Gooi and KM Thompson. Differences in the characteristics of human monoclonal and polyclonal anti-D as revealed by immunochemical investigations: human monoclonal antibodies share specificities with natural antibodies. Transfus Med 2, 151-157 (1992).
KM Thompson, J Sutherland, G Barden, MD Melamed, MG Wright, SW Bailey and SJ Thorpe. Human monoclonal antibodies specific for blood group antigens demonstrate multispecific properties characteristic of natural autoantibodies. Immunology 76, 146-157 (1992).
SJ Thorpe and SW Bailey. Demonstration of autoreactivity by a human monoclonal IgG anti-Rh D antibody. Br J Haematol 83, 311-318 (1993).
MC McCann, M Bruce, EM Shaw, SJ Thorpe, SS Armstrong and K James. The production and evaluation of two human monoclonal anti-D antibodies. Transfusion Medicine 3, 187-194 (1993).
I Randen, KM Thompson, SJ Thorpe, O Forre and JB Nativig. Human monoclonal IgG rheumatoid factors from the synovial tissue of patients with rheumatoid arthritis. Scand J Immunol 37, 668-672 (1993).
JD Marks, WH Ouwehand, JM Bye, R Finnern, BD Gorick, D Voak, SJ Thorpe, NC Hughes-Jones and G Winter. Human antibody fragments specific for human blood group antigens from a phage display library. Bio/Technology 11, 1145-1149 (1993).
SJ Thorpe, M Borretzen, SW Bailey, I Randen, JB Nativig and KM Thompson. Human monoclonal rheumatoid factors: incidence of cross-reactions with tissue components and correlation with V_H gene usage. Immunology 83, 114-121 (1994).
SJ Thorpe, CE Boult, SW Bailey and KM Thompson. The basis of unexpected cross-reactions shown by human monoclonal antibodies against blood group antigens as revealed by immunohistochemistry. Applied Immunohistochem 4, 190-200 (1996).
SJ Thorpe. Tissue reactivities of human monoclonal anti-Rh antibodies. Biotest Bulletin 5, 523-528 (1997).
SJ Thorpe, CE Boult and KM Thompson. Immunochemical characterization of the Rh C^w antigen using human monoclonal antibodies. Vox Sang 73, 174-181 (1997).
SJ Thorpe, CE Boult, FK Stevenson, ML Scott, J Sutherland, MB Spellerberg, JB Natvig and KM Thompson. Cold agglutinin activity is common among human monoclonal IgM Rh system antibodies using the V_4-34 heavy chain variable gene segment. Transfusion 37, 1111-1116 (1997).
SJ Thorpe, CE Turner, FK Stevenson, MB Spellerberg, R Thorpe, JB Natvig and KM Thompson. V_4-34-encoded human monoclonal antibodies: cold agglutinin activity is a common property whereas the multireactive phenotype correlates with predicted charge. Immunology 93, 129-136 (1998).
SS Armstrong-Fisher, MC McCann Carter, I Downing, RH Fraser, GE Inglis, EK Allan, A Mackie, CV Prowse, JG Templeton, SJ Thorpe and SJ Urbaniak. Evaluation of a panel of human monoclonal antibodies to Rh D antigen and exploration of the synergistic effects of blending IgG1 and IgG3 antibodies on their in vitro biological function. Transfusion 39, 1005-1012 (1999).
SJ Thorpe, C Turner, A Heath, I Feavers, I Vatn, JB Natvig and K Thompson. Clonal analysis of a human anti-mouse antibody (HAMA) response. Scandinavian Journal of Immunology 57, 85-92 (2003).
SJ Thorpe, B Fox, C Turner and M Scott. Competitive enzyme-linked immunoassay of IgG monoclonal anti-D. Transfusion Medicine 13, 153-159 (2003).
M Frøyland, KM Thompson, SJ Thorpe, SS Sahota, T Gedde-Dahl and B Bogen. A VH4-34+ myeloma protein with weak autoreactivity. Haematologica 92, 696-699 (2007).
R Stebbings, L Findlay, C Edwards, D Eastwood, C Bird, D North, Y Mistry, P Dilger, E Liefooghe, I Cludts, B Fox, G Tarrant, J Robinson, T Meager, C Dolman, SJ Thorpe, A Bristow, M Wadhwa, R Thorpe and S Poole. ‘Cytokine storm’ in the phase I trial of monoclonal antibody TGN1412: better understanding the causes to improve preclinical testing of immunotherapeutics. J Immunol 179, 3325-3331 (2007).
SJ Thorpe, C Ball, B Fox, KM Thompson, R Thorpe and A Bristow. Anti-Rh D and anti-i activities are inseparable in V_4-34-encoded monoclonal anti-Rh D: the same framework 1 residues are required for both reactivities. Transfusion 48, 930-940 (2008).
AF Labrijn, AO Buijsse, ETJ van den Bremer, AYW Verwilligen, SJ Thorpe, J Killestein, CH Polman, RC Aalberse, J Schuurman, JGJ van de Winkel and PWHI Parren. Therapeutic IgG4 antibodies engage in Fab-arm exchange with patients’ IgG4 in vivo. Nature Biotech 27, 767-71 (2009).