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Publications

 

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Relevant Publications

 

  1. SJ Thorpe.  Detection of Rh D-associated epitopes in human and animal tissues using human monoclonal anti-D antibodies.  Br J Haematol 73, 527-536 (1989).
  2. SJ Thorpe.  Reactivity of a human monoclonal antibody against Rh D with the intermediate filament protein vimentin.  Br J Haematol 76, 116-120 (1990).
  3. SJ Thorpe, SW Bailey, HC Gooi and KM Thompson.  Differences in the characteristics of human monoclonal and polyclonal anti-D as revealed by immunochemical investigations: human monoclonal antibodies share specificities with natural antibodies.  Transfus Med 2, 151-157 (1992).
  4. KM Thompson, J Sutherland, G Barden, MD Melamed, MG Wright, SW Bailey and SJ Thorpe.  Human monoclonal antibodies specific for blood group antigens demonstrate multispecific properties characteristic of natural autoantibodies.  Immunology 76, 146-157 (1992).
  5. SJ Thorpe and SW Bailey.  Demonstration of autoreactivity by a human monoclonal IgG anti-Rh D antibody.  Br J Haematol 83, 311-318 (1993).
  6. MC McCann, M Bruce, EM Shaw, SJ Thorpe, SS Armstrong and K James.  The production and evaluation of two human monoclonal anti-D antibodies.  Transfusion Medicine 3, 187-194 (1993).
  7. I Randen, KM Thompson, SJ Thorpe, O Forre and JB Nativig.  Human monoclonal IgG rheumatoid factors from the synovial tissue of patients with rheumatoid arthritis.  Scand J Immunol 37, 668-672 (1993).
  8. JD Marks, WH Ouwehand, JM Bye, R Finnern, BD Gorick, D Voak, SJ Thorpe, NC Hughes-Jones and G Winter.  Human antibody fragments specific for human blood group antigens from a phage display library.  Bio/Technology 11, 1145-1149 (1993).
  9. SJ Thorpe, M Borretzen, SW Bailey, I Randen, JB Nativig and KM Thompson.  Human monoclonal rheumatoid factors: incidence of cross-reactions with tissue components and correlation with VH gene usage.  Immunology 83, 114-121 (1994).
  10. SJ Thorpe, CE Boult, SW Bailey and KM Thompson.  The basis of unexpected cross-reactions shown by human monoclonal antibodies against blood group antigens as revealed by immunohistochemistry.  Applied Immunohistochem 4, 190-200 (1996).
  11. SJ Thorpe.  Tissue reactivities of human monoclonal anti-Rh antibodies.  Biotest Bulletin 5, 523-528 (1997).
  12. SJ Thorpe, CE Boult and KM Thompson.  Immunochemical characterization of the Rh Cw antigen using human monoclonal antibodies.  Vox Sang 73, 174-181 (1997).
  13. SJ Thorpe, CE Boult, FK Stevenson, ML Scott, J Sutherland, MB Spellerberg, JB Natvig and KM Thompson.  Cold agglutinin activity is common among human monoclonal IgM Rh system antibodies using the V4-34 heavy chain variable gene segment.  Transfusion 37, 1111-1116 (1997).
  14. SJ Thorpe, CE Turner, FK Stevenson, MB Spellerberg, R Thorpe, JB Natvig and KM Thompson.  V4-34-encoded human monoclonal antibodies: cold agglutinin activity is a common property whereas the multireactive phenotype correlates with predicted charge.  Immunology 93, 129-136 (1998).
  15. SS Armstrong-Fisher, MC McCann Carter, I Downing, RH Fraser, GE Inglis, EK Allan, A Mackie, CV Prowse, JG Templeton, SJ Thorpe and SJ Urbaniak.  Evaluation of a panel of human monoclonal antibodies to Rh D antigen and exploration of the synergistic effects of blending IgG1 and IgG3 antibodies on their in vitro biological function.  Transfusion 39, 1005-1012 (1999).
  16. SJ Thorpe, C Turner, A Heath, I Feavers, I Vatn, JB Natvig and K Thompson.  Clonal analysis of a human anti-mouse antibody (HAMA) response.  Scandinavian Journal of Immunology 57, 85-92 (2003).
  17. SJ Thorpe, B Fox, C Turner and M Scott.  Competitive enzyme-linked immunoassay of IgG monoclonal anti-D.  Transfusion Medicine 13, 153-159 (2003).
  18. M Frøyland, KM Thompson, SJ Thorpe, SS Sahota, T Gedde-Dahl and B Bogen.  A VH4-34+ myeloma protein with weak autoreactivity.  Haematologica 92, 696-699 (2007).  
  19. R Stebbings, L Findlay, C Edwards, D Eastwood, C Bird, D North, Y Mistry, P Dilger, E Liefooghe, I Cludts, B Fox, G Tarrant, J Robinson, T Meager, C Dolman, SJ Thorpe, A Bristow, M Wadhwa, R Thorpe and S Poole.  ‘Cytokine storm’ in the phase I trial of monoclonal antibody TGN1412: better understanding the causes to improve preclinical testing of immunotherapeutics.  J Immunol 179, 3325-3331 (2007).
  20. SJ Thorpe, C Ball, B Fox, KM Thompson, R Thorpe and A Bristow.  Anti-Rh D and anti-i activities are inseparable in V4-34-encoded monoclonal anti-Rh D: the same framework 1 residues are required for both reactivities.  Transfusion 48, 930-940 (2008).
  21. AF Labrijn, AO Buijsse, ETJ van den Bremer, AYW Verwilligen, SJ Thorpe, J Killestein, CH Polman, RC Aalberse, J Schuurman, JGJ van de Winkel and PWHI Parren.  Therapeutic IgG4 antibodies engage in Fab-arm exchange with patients’ IgG4 in vivo.  Nature Biotech 27, 767-71 (2009).

 



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